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Charlotte Guyomar

Charlotte Guyomar
Postdoctoral Fellow
PhD, Institute of Genetics and Development of Rennes (IGDR)
MSc in Fundamental and applied microbiology, University of Rennes 1
Bsc in Biology, University of Rennes 1
Numerous cultivated and uncultivated viruses encode ribosomal proteins.
Mizuno CM*, Guyomar C*, Roux S, Lavigne R, Rodriguez-Valera F, Sullivan M, Gillet R, Forterre P, Krupovic M. *Joint first authorship
Nature Communications (in press)
A genetic tool to quantify trans-Translation activity in vivo.
Macé K, Demay F, Guyomar C, Georgeault S, Giudice E, Goude R, Trautwetter A, Ermel G, Blanco C, Gillet R.
J Mol Biol. 2017 Nov 24;429(23):3617-3625. doi: 10.1016/j.jmb.2017.10.007. Epub 2017 Oct 13.
Genomic and physiological analysis reveals versatile metabolic capacity of deep-sea Photobacterium phosphoreum ANT-2200.
Zhang SD, Santini CL, Zhang WJ, Barbe V, Mangenot S, Guyomar C, Garel M, Chen HT, Li XG, Yin QJ, Zhao Y, Armengaud J, Gaillard JC, Martini S, Pradel N, Vidaud C, Alberto F, Médigue C, Tamburini C, Wu LF.
Extremophiles. 2016 May;20(3):301-10. doi: 10.1007/s00792-016-0822-1. Epub 2016 Apr 2.
Charlotte carried out her PhD in Reynald Gillet’s team at the Institute of Genetics and Development of Rennes (IGDR), where she investigated bacteriophages and ribosome-like proteins (in collaboration with Mart Krupovic at the Paris Pasteur Institute). In particular, she worked on the bacterial ribosome rescue system called trans-translation. Charlotte's main past experience is in cryo-EM (in particular single particle analysis), which she used to characterize the trans-translation machinery. Charlotte also developed an in vitro assay to screen for anti trans-translation drugs.